Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 2/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Malonic Acid SCHEMBL8552650 | 0.94 | SMN1; SMN2 (0.34) | SMN1; SMN2LMNARAB9AMTNR1AMTNR1B | |
| Malonic Acid SCHEMBL8549235 | 0.85 | MAPT (0.36) | SMN1; SMN2LMNARAB9AMTNR1AMTNR1B | |
| Malonic Acid SCHEMBL7146355 | 0.85 | HTR1D (0.43) | SMN1; SMN2LMNAMTNR1AMTNR1BMAPT | |
| Malonic Acid SCHEMBL8548541 | 0.80 | MAPT (0.35) | SMN1; SMN2LMNARAB9AMTNR1AMTNR1B | |
| Malonic Acid SCHEMBL7147604 | 0.79 | KDM4E (0.44) | SMN1; SMN2LMNAMTNR1AMTNR1BMAPT | |
| SCHEMBL8551217 | 0.77 | GNRHR (0.37) | SMN1; SMN2LMNAKDM4EHPGDTSHR | |
| SCHEMBL8553337 | 0.72 | GNRHR (0.34) | SMN1; SMN2KDM4E | |
| Citric Acid SCHEMBL8702317 | 0.68 | TRPV1 (0.45) | SMN1; SMN2LMNAMAPTHTT | |
| Benzoic Acid SCHEMBL8551806 | 0.66 | MEN1 (0.31) | LMNANPSR1 | |
| SCHEMBL28382188 | 0.66 | PARP1 (0.56) | MTNR1AMTNR1BHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |