Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 4/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542353 | 0.90 | ITGB3 (0.48) | ITGB3ITGA2BHDAC3HDAC1F10 | |
| Hydrochloric Acid SCHEMBL6786102 | 0.90 | ITGB3 (0.47) | ITGB3ITGA2BHDAC3HDAC1F10 | |
| Hydrochloric Acid SCHEMBL8542083 | 0.89 | ITGB3 (0.47) | ITGB3ITGA2BHDAC3HDAC1F10 | |
| SCHEMBL8548990 | 0.86 | ITGB3 (0.45) | ITGB3ITGA2BHDAC3HDAC1F10 | |
| Hydrochloric Acid SCHEMBL7406826 | 0.84 | ITGB3 (0.43) | ITGB3ITGA2BHDAC3HDAC1F10 | |
| SCHEMBL6792717 | 0.84 | ITGB3 (0.48) | ITGB3ITGA2BNAMPT | |
| SCHEMBL6793529 | 0.82 | CCR1 (0.44) | ITGB3ITGA2BF10GFERSMN1; SMN2 | |
| SCHEMBL6790212 | 0.82 | ITGB3 (0.60) | ITGB3ITGA2BHDAC3HDAC1F10 | |
| SCHEMBL6792152 | 0.81 | ITGB3 (0.69) | ITGB3ITGA2BF10GFERSMN1; SMN2 | |
| SCHEMBL6791068 | 0.80 | F10 (0.44) | ITGB3ITGA2BF10SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783500-B1 | AMINOHETEROCYCLIC DERIVATIVES AS ANTITHROMBOTIC OR ANTICOAGULANT AGENTS | ZENECA LTD (GB) | 1998-07-22 | — | — | EP | disclosed |