Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542353 | 0.92 | ITGB3 (0.48) | ITGB3ITGA2BALDH1A1KDM4ENPSR1 | |
| Hydrochloric Acid SCHEMBL8542083 | 0.91 | ITGB3 (0.47) | ITGB3ITGA2BALDH1A1KDM4ENPSR1 | |
| Hydrochloric Acid SCHEMBL7406826 | 0.87 | ITGB3 (0.43) | ITGB3ITGA2BALDH1A1KDM4ENPSR1 | |
| SCHEMBL8548825 | 0.86 | ITGB3 (0.48) | ITGB3ITGA2BNPSR1KMT2ANAMPT | |
| Hydrochloric Acid SCHEMBL6786102 | 0.83 | ITGB3 (0.47) | ITGB3ITGA2BKMT2AMEN1F10 | |
| SCHEMBL8543970 | 0.82 | F10 (0.38) | ITGB3ITGA2BTSHRF10 | |
| SCHEMBL6792717 | 0.82 | ITGB3 (0.48) | ITGB3ITGA2BKDM4ENAMPT | |
| SCHEMBL6790212 | 0.79 | ITGB3 (0.60) | ITGB3ITGA2BKDM4ENPSR1KMT2A | |
| SCHEMBL6792152 | 0.79 | ITGB3 (0.69) | ITGB3ITGA2BF10 | |
| SCHEMBL6793529 | 0.79 | CCR1 (0.44) | ITGB3ITGA2BKMT2AMEN1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783500-B1 | AMINOHETEROCYCLIC DERIVATIVES AS ANTITHROMBOTIC OR ANTICOAGULANT AGENTS | ZENECA LTD (GB) | 1998-07-22 | — | — | EP | disclosed |