Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL614374 | 0.72 | — | — | |
| SCHEMBL1059359 | 0.69 | — | — | |
| SCHEMBL13767655 | 0.67 | SLC18A3 (0.36) | BCHEACHE | |
| SCHEMBL3441311 | 0.66 | HRH1 (0.31) | — | |
| SCHEMBL2260651 | 0.66 | — | — | |
| SCHEMBL2504923 | 0.66 | — | — | |
| SCHEMBL2260259 | 0.66 | — | — | |
| SCHEMBL1012583 | 0.66 | — | — | |
| SCHEMBL4262104 | 0.66 | HPGDS (0.39) | — | |
| Bromide SCHEMBL2984494 | 0.65 | HPGDS (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711291-B1 | N-(PIPERIDINYL-1-ALKYL)-SUBSTITUTED CYCLOHEXANE CARBOXYLIC ACID AMIDES AS 5-HT1A RECEPTOR ANTAGONISTS | WYETH JOHN & BROTHER LTD (GB) | 1998-11-25 | — | — | EP | disclosed |
| US-5763460-A | N-(piperidinyl-1-alkyl)-substituted cyclohexane carboxylic acid amides as 5-htia receptor antagonists | JOHN WYETH & BROTHER LIMITED (US) | 1998-06-09 | — | — | US | disclosed |
| EP-0711291-A1 | N-(PIPERIDINYL-1-ALKYL)-SUBSTITUTED CYCLOHEXANE CARBOXYLIC ACID AMIDES AS 5-HT1A RECEPTOR ANTAGONISTS | JOHN WYETH & BROTHER LIMITED (GB) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995002592-A1 | N-(PIPERIDINYL-1-ALKYL)-SUBSTITUTED CYCLOHEXANE CARBOXYLIC ACID AMIDES AS 5-HT1A RECEPTOR ANTAGONISTS | JOHN WYETH & BROTHER LTD. (GB) | 1995-01-26 | — | — | WO | disclosed |