Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL2984494 | 0.99 | HPGDS (0.38) | HPGDSBAZ2AMEN1KMT2A | |
| SCHEMBL2976442 | 0.83 | OGA (0.33) | — | |
| SCHEMBL2969142 | 0.83 | — | — | |
| SCHEMBL7238218 | 0.78 | MAPT (0.31) | MEN1KMT2A | |
| SCHEMBL4828410 | 0.69 | — | — | |
| SCHEMBL3441311 | 0.69 | HRH1 (0.31) | — | |
| SCHEMBL3544509 | 0.66 | HTR1A (0.33) | — | |
| SCHEMBL8548883 | 0.66 | BCHE (0.30) | — | |
| SCHEMBL14746442 | 0.66 | MEN1 (0.48) | MEN1KMT2A | |
| SCHEMBL20195251 | 0.66 | HPGDS (0.52) | HPGDSBAZ2AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945635-B1 | THIAZOLYL PIPERIDINE DERIVATIVES USEFUL AS H3 RECEPTOR MODULATORS | HOFFMANN LA ROCHE (CH) | 2009-05-06 | — | — | EP | disclosed |