Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 13/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8719187 | 1.00 | ALOX15 (0.47) | ALOX15 | |
| SCHEMBL8544547 | 0.89 | ALOX15 (0.41) | ALOX15 | |
| SCHEMBL8547075 | 0.87 | ALOX15 (0.49) | ALOX15 | |
| SCHEMBL8544259 | 0.86 | TUBB4A (0.43) | ALOX15 | |
| SCHEMBL8544261 | 0.86 | TUBB4A (0.43) | ALOX15 | |
| SCHEMBL7863130 | 0.85 | PARP1 (0.38) | ALOX15 | |
| SCHEMBL8929778 | 0.85 | PARP1 (0.38) | ALOX15 | |
| SCHEMBL8546080 | 0.83 | PARP1 (0.41) | ALOX15 | |
| SCHEMBL8546083 | 0.83 | PARP1 (0.41) | ALOX15 | |
| SCHEMBL8930082 | 0.80 | MAPT (0.48) | ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702673-B1 | BENZ(B)AZEPINE-2,5-DIONES USEFUL IN THE TREATMENT OF NEURODEGENERATIVE DISORDERS | ZENECA LTD (GB) | 1998-02-25 | — | — | EP | claimed |
| US-5801168-A | NMDA RECEPTOR ANTAGONISTS | ZENECA LIMITED (GB) | 1998-09-01 | — | — | US | disclosed |
| US-5656626-A | NERVOUS SYSTEM OR BRAIN DISORDERS; BENZ(B)AZEPINE | ZENECA LIMITED (GB) | 1997-08-12 | — | — | US | disclosed |
| EP-0702673-A1 | BENZ(B)AZEPINE-2,5-DIONES USEFUL IN THE TREATMENT OF NEURODEGENERATIVE DISORDERS | ZENECA LIMITED (GB) | 1996-03-27 | — | — | EP | disclosed |
| WO-1994029275-A1 | BENZ(B)AZEPINE-2,5-DIONES USEFUL IN THE TREATMENT OF NEURODEGENERATIVE DISORDERS | ZENECA LIMITED (GB) | 1994-12-22 | — | — | WO | disclosed |