Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547944 | 0.92 | EDNRB (0.44) | EDNRBEDNRA | |
| SCHEMBL8553569 | 0.91 | EDNRB (0.54) | EDNRBEDNRA | |
| SCHEMBL8548900 | 0.90 | EDNRB (0.53) | EDNRBEDNRA | |
| SCHEMBL8548125 | 0.89 | EDNRB (0.45) | EDNRBEDNRA | |
| SCHEMBL8655565 | 0.88 | EDNRB (0.45) | EDNRBEDNRA | |
| SCHEMBL8545781 | 0.87 | EDNRB (0.44) | EDNRBEDNRA | |
| SCHEMBL8546601 | 0.86 | EDNRB (0.51) | EDNRBEDNRA | |
| SCHEMBL8551995 | 0.85 | EDNRB (0.41) | EDNRBEDNRA | |
| SCHEMBL8551102 | 0.85 | EDNRB (0.45) | EDNRBEDNRA | |
| SCHEMBL8551085 | 0.84 | EDNRB (0.45) | EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863898-A1 | ENDOTHELIN RECEPTOR ANTAGONISTS | MERCK PATENT GmbH (DE) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997019077-A1 | ENDOTHELIN RECEPTOR ANTAGONISTS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1997-05-29 | — | — | WO | disclosed |