Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 5/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.40 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551891 | 0.97 | HTR1F (0.49) | HTR1FNAMPTHDAC1MAPK1PDPK1 | |
| Malonic Acid SCHEMBL8215354 | 0.83 | HTR1F (0.70) | HTR1FNAMPTHDAC1MAPK1MAPT | |
| SCHEMBL8196218 | 0.79 | HTR1F (0.75) | HTR1FNAMPTMAPK1MAPTALDH1A1 | |
| SCHEMBL7141203 | 0.73 | HTR1F (0.73) | HTR1FNAMPTHDAC1MAPK1MAPT | |
| SCHEMBL8551441 | 0.72 | ACKR3 (0.49) | HTR1FHDAC1MAPK1PDPK1CHEK2 | |
| SCHEMBL7140234 | 0.72 | HTR1F (0.77) | HTR1FMAPK1PDPK1CHEK2ABL1 | |
| SCHEMBL8553688 | 0.72 | HTR1F (0.42) | HTR1FACKR3MAPTCTNNB1TCF7L2 | |
| Hydrochloric Acid SCHEMBL7140335 | 0.71 | HTR1F (0.76) | HTR1FMAPK1PDPK1CHEK2ABL1 | |
| SCHEMBL8551217 | 0.70 | GNRHR (0.37) | HDAC1ALDH1A1SMN1; SMN2KDM4ETDP1 | |
| SCHEMBL8552249 | 0.69 | F2R (0.43) | HTR1FNAMPTMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998015545-A1 | NEW SEROTONIN 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-04-16 | — | — | WO | disclosed |
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |