Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 3/20 | 0.43 |
| ▸ | HTR1F | P30939 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 3/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8194633 | 0.83 | HTR1F (0.59) | F2RHTR1FMAPTALDH1A1KDM4E | |
| SCHEMBL8551891 | 0.72 | HTR1F (0.49) | HTR1FMAPTALDH1A1KDM4ENAMPT | |
| Malonic Acid SCHEMBL8548925 | 0.69 | HTR1F (0.47) | HTR1FMAPTALDH1A1KDM4ENAMPT | |
| SCHEMBL17142560 | 0.65 | F2R (0.55) | F2RMAPTALDH1A1LMNA | |
| SCHEMBL8547156 | 0.65 | HTR1F (0.49) | HTR1FMAPTPOLB | |
| SCHEMBL8553688 | 0.64 | HTR1F (0.42) | HTR1FMAPTALDH1A1KDM4EPOLB | |
| SCHEMBL17148222 | 0.62 | F2R (0.54) | F2RMAPTALDH1A1POLBLMNA | |
| SCHEMBL8551441 | 0.61 | ACKR3 (0.49) | HTR1FTRPV1MAPT | |
| SCHEMBL10069477 | 0.61 | F2R (1.00) | F2R | |
| SCHEMBL8549211 | 0.61 | HTR1F (0.49) | HTR1FMAPTALDH1A1KDM4EPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998015545-A1 | NEW SEROTONIN 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-04-16 | — | — | WO | disclosed |
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |