Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 17/20 | 0.69 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13379588 | 0.83 | DRD2 (0.51) | F2DRD2DRD4DRD3ADRB3 | |
| SCHEMBL13355728 | 0.82 | DRD2 (0.50) | F2DRD2DRD4DRD3ADRB3 | |
| SCHEMBL8543078 | 0.81 | F2 (1.00) | F2 | |
| SCHEMBL8544231 | 0.81 | F2 (1.00) | F2 | |
| SCHEMBL15945993 | 0.80 | DRD2 (0.47) | F2DRD2DRD4DRD3ADRB3 | |
| Hydrochloric Acid SCHEMBL8542002 | 0.80 | F2 (0.98) | F2 | |
| SCHEMBL7336884 | 0.80 | GALR3 (0.64) | GALR3HSP90AA1 | |
| SCHEMBL3125560 | 0.79 | DRD2 (0.46) | F2DRD2DRD4DRD3ADRB3 | |
| SCHEMBL8546481 | 0.79 | F2 (0.65) | F2ADRB3ADRA1A | |
| Hydrochloric Acid SCHEMBL8543551 | 0.78 | F2 (0.98) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687253-B1 | 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-16 | — | — | EP | disclosed |