Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.33 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | MUS81 | Q96NY9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL855131 | 0.93 | TSHR (0.57) | TSHRALDH1A1 | |
| SCHEMBL21861 | 0.84 | TSHR (1.00) | TSHRALDH1A1UCHL1UCHL3ECE1 | |
| SCHEMBL30354042 | 0.84 | TSHR (1.00) | TSHRALDH1A1UCHL1UCHL3ECE1 | |
| SCHEMBL855118 | 0.82 | TSHR (0.65) | TSHRALDH1A1 | |
| Water SCHEMBL28019026 | 0.82 | TSHR (0.94) | TSHRALDH1A1UCHL1UCHL3ECE1 | |
| SCHEMBL854488 | 0.81 | TSHR (0.56) | TSHRALDH1A1 | |
| SCHEMBL18789227 | 0.77 | ALDH1A1 (0.65) | TSHRALDH1A1UCHL1UCHL3ECE1 | |
| SCHEMBL8995862 | 0.76 | TSHR (0.82) | TSHRALDH1A1UCHL1UCHL3ECE1 | |
| SCHEMBL29362800 | 0.73 | ALDH1A1 (0.43) | TSHRALDH1A1 | |
| SCHEMBL335922 | 0.73 | ALDH1A1 (0.43) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2433933-B1 | PRODUCTION METHOD OF TRI- OR TETRAHALOGEN-SUBSTITUTED PHTHALIDE | SUMITOMO CHEMICAL CO (JP) | 2019-05-08 | — | — | EP | disclosed |
| CN-105849094-A | Method for producing halogen-substituted phthalide | 住友化学株式会社 | 2016-08-10 | — | — | CN | disclosed |
| US-8604221-B2 | Production method of halogen-substituted phthalide | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-12-10 | — | — | US | disclosed |
| US-20120142946-A1 | PRODUCTION METHOD OF HALOGEN-SUBSTITUTED PHTHALIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-06-07 | — | — | US | disclosed |
| EP-2433933-A1 | PRODUCTION METHOD OF HALOGEN-SUBSTITUTED PHTHALIDE | Sumitomo Chemical Company, Limited (JP) | 2012-03-28 | — | — | EP | disclosed |