Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.64 |
| ▸ | CTSK | P43235 | 2/20 | 0.64 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | ANPEP | P15144 | 1/20 | 0.59 |
| ▸ | BACE1 | P56817 | 9/20 | 0.59 |
| ▸ | CTSL | P07711 | 1/20 | 0.57 |
| ▸ | CTSB | P07858 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549086 | 1.00 | CTSS (0.64) | CTSSCTSKCA2ANPEPBACE1 | |
| SCHEMBL4750042 | 0.89 | CTSS (0.61) | CTSSCTSKBACE1 | |
| SCHEMBL9006099 | 0.88 | CA2 (0.74) | CTSSCTSKCA2BACE1CTSL | |
| SCHEMBL9006092 | 0.88 | CA2 (0.74) | CTSSCTSKCA2BACE1CTSL | |
| SCHEMBL9128016 | 0.87 | TP53 (0.62) | CTSSCTSKCA2BACE1KMT2A | |
| SCHEMBL9128031 | 0.87 | TP53 (0.62) | CTSSCTSKCA2BACE1KMT2A | |
| SCHEMBL29472197 | 0.85 | CTSS (0.63) | CTSSCTSKCA2BACE1CTSL | |
| SCHEMBL29460401 | 0.84 | CTSS (0.65) | CTSSCTSKCA2CTSLCTSB | |
| SCHEMBL2393583 | 0.83 | BACE1 (0.59) | CTSSCTSKBACE1CTSLCTSB | |
| SCHEMBL29253632 | 0.83 | BACE1 (0.59) | CTSSCTSKBACE1CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |
| US-5686424-A | FOR TREATING INFLAMMATION | MILES INC. (US) | 1997-11-11 | — | — | US | disclosed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | disclosed |