SCHEMBL8549110

SCHEMBL8549110

CC(=O)Nc1ccc2cc3ccccc3cc2c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 8/20 0.62
KMT2A Q03164 7/20 0.62
MAPT P10636 7/20 0.62
NPC1 O15118 7/20 0.62
MEN1 O00255 6/20 0.62
KDM4E B2RXH2 3/20 0.62
GLA P06280 1/20 0.62
TNNI3 P19429 1/20 0.62
TNNT2 P45379 1/20 0.62
TNNC1 P63316 1/20 0.62
RUNX1 Q01196 1/20 0.62
CBFB Q13951 1/20 0.62
ALDH1A1 P00352 4/20 0.62
CYP1A2 P05177 2/20 0.62
CYP2C19 P33261 1/20 0.62
HIF1A Q16665 1/20 0.62
PABPC1 P11940 1/20 0.59
L3MBTL1 Q9Y468 2/20 0.56
POLB P06746 2/20 0.56
HSD17B10 Q99714 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Anthracene SCHEMBL29076817 0.96 MEN1 (0.67) RAB9AKMT2AMAPTNPC1MEN1
SCHEMBL1176635 0.94 MEN1 (0.69) RAB9AKMT2AMAPTNPC1MEN1
SCHEMBL8577441 0.90 MEN1 (0.68) RAB9AKMT2AMAPTNPC1MEN1
SCHEMBL8576078 0.88 MEN1 (0.66) RAB9AKMT2AMAPTNPC1MEN1
SCHEMBL28154187 0.85 MEN1 (0.55) RAB9AKMT2AMAPTNPC1MEN1
SCHEMBL28506855 0.85 TDP1 (0.60) RAB9AKMT2AMAPTNPC1MEN1
SCHEMBL6746166 0.84 MAPT (0.62) RAB9AKMT2AMAPTNPC1MEN1
SCHEMBL6138266 0.82 MAPT (0.60) RAB9AKMT2AMAPTNPC1MEN1
SCHEMBL13609717 0.82 TDP1 (0.57) RAB9AKMT2AMAPTNPC1MEN1
SCHEMBL3952992 0.81 KMT2A (0.60) RAB9AKMT2AMAPTNPC1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10256412-B2 Anthracene-based compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2019-04-09 US disclosed
US-10256412-B2 Anthracene-based compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2019-04-09 US disclosed
US-20150048321-A1 ANTHRACENE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-02-19 US disclosed
US-20150048321-A1 ANTHRACENE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-02-19 US disclosed
US-20150048321-A1 ANTHRACENE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-02-19 US disclosed
US-8709307-B2 Laser protection polymeric materials OXAZOGEN, INC. (US) 2014-04-29 US disclosed
US-20110012074-A1 LASER PROTECTION POLYMERIC MATERIALS OXAZOGEN INC. (US) 2011-01-20 US disclosed
EP-0536208-B1 1,2-DIHYDRO-3H-DIBENZISOQUINOLINE-1,3-DIONE ANTICANCER AGENTS RES CORP TECHNOLOGIES INC (US) 1998-01-21 EP disclosed
US-5635506-A ANTITUMOR AGENTS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1997-06-03 US disclosed
EP-0660824-A1 1,2 DIHYDRO-3-H-DIBENZ(de,h) ISOQUINOLINE 1,3 DIONE AND THEIR USE AS ANTICANCER AGENTS RESEARCH CORPORATION TECHNOLOGIES (US) 1995-07-05 EP disclosed
WO-1994006771-A9 1,2 DIHYDRO-3-H-DIBENZ(de,h) ISOQUINOLINE 1,3 DIONE AND THEIR USE AS ANTICANCER AGENTS 1994-06-09 WO disclosed
WO-1994006771-A1 1,2 DIHYDRO-3-H-DIBENZ(de,h) ISOQUINOLINE 1,3 DIONE AND THEIR USE AS ANTICANCER AGENTS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1994-03-31 WO disclosed
EP-0536208-A4 1,2-DIHYDRO-3H-DIBENZISOQUINOLINE-1,3-DIONE ANTICANCER AGENTS 1993-05-05 EP disclosed
EP-0536208-A1 1,2-DIHYDRO-3H-DIBENZISOQUINOLINE-1,3-DIONE ANTICANCER AGENTS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1993-04-14 EP disclosed
WO-1992000281-A1 1,2-DIHYDRO-3H-DIBENZISOQUINOLINE-1,3-DIONE ANTICANCER AGENTS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1992-01-09 WO disclosed