Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | GLA | P06280 | 1/20 | 0.68 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.68 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.68 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.68 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.68 |
| ▸ | CBFB | Q13951 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | BRD4 | O60885 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8576078 | 0.93 | MEN1 (0.66) | MEN1KMT2AKDM4EMAPTRAB9A | |
| SCHEMBL1176635 | 0.92 | MEN1 (0.69) | MEN1KMT2AKDM4EMAPTRAB9A | |
| SCHEMBL17919672 | 0.90 | TDP1 (0.64) | MEN1KMT2AKDM4EMAPTRAB9A | |
| SCHEMBL1808467 | 0.90 | MEN1 (0.64) | MEN1KMT2AKDM4EMAPTRAB9A | |
| Anthracene SCHEMBL29076817 | 0.90 | MEN1 (0.67) | MEN1KMT2AKDM4EMAPTRAB9A | |
| SCHEMBL8549110 | 0.90 | RAB9A (0.62) | MEN1KMT2AKDM4EMAPTRAB9A | |
| SCHEMBL1808465 | 0.90 | MEN1 (0.58) | MEN1KMT2AKDM4EMAPTRAB9A | |
| SCHEMBL22815990 | 0.88 | MEN1 (0.56) | MEN1KMT2AKDM4EMAPTRAB9A | |
| SCHEMBL12298751 | 0.88 | MEN1 (0.56) | MEN1KMT2AKDM4EMAPTRAB9A | |
| SCHEMBL21765699 | 0.87 | RAB9A (0.72) | MEN1KMT2AKDM4EMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998014501-A1 | PROCESS FOR THE PREPARATION OF THERMOTROPIC AROMATIC POLYESTERS DIRECTLY FROM DIALKYL AROMATIC ESTERS | HOECHST CELANESE CORPORATION (US) | 1998-04-09 | — | — | WO | claimed |
| US-5731401-A | ONE STEP; HIGH MOLECULAR WEIGHT | HOECHST CELANESE CORP. (US) | 1998-03-24 | — | — | US | claimed |
| US-4883915-A | TO AMIDES, BOROSILICATE MOLECULAR SIEVE | AMOCO CORPORATION (US) | 1989-11-28 | — | — | US | claimed |
| US-7803804-B2 | Substituted pyrazines for use in the treatment of inflammatory or allergic conditions | NOVARTIS AG (CH) | 2010-09-28 | — | — | US | disclosed |
| US-7803804-B2 | Substituted pyrazines for use in the treatment of inflammatory or allergic conditions | NOVARTIS AG (CH) | 2010-09-28 | — | — | US | disclosed |
| US-20080312217-A1 | Organic Compounds | NOVARTIS AG | 2008-12-18 | — | — | US | disclosed |
| US-20080312217-A1 | Organic Compounds | NOVARTIS AG | 2008-12-18 | — | — | US | disclosed |
| WO-1998014501-A1 | PROCESS FOR THE PREPARATION OF THERMOTROPIC AROMATIC POLYESTERS DIRECTLY FROM DIALKYL AROMATIC ESTERS | HOECHST CELANESE CORPORATION (US) | 1998-04-09 | — | — | WO | disclosed |
| US-5731401-A | ONE STEP; HIGH MOLECULAR WEIGHT | HOECHST CELANESE CORP. (US) | 1998-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312217-A1 | Organic Compounds | TRPA1, TRPV1, CHRM1 | MEN1 1118/4885KMT2A 3363/4885KDM4E 4641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.