Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | ESRRA | P11474 | 1/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 2/20 | 0.53 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.53 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.53 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.53 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.53 |
| ▸ | CBFB | Q13951 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6138266 | 0.98 | MAPT (0.60) | MAPTALDH1A1HPGDKMT2AKDM4E | |
| SCHEMBL7820599 | 0.92 | MAOA (0.61) | MAPTALDH1A1HPGDKMT2AKDM4E | |
| SCHEMBL3952992 | 0.91 | KMT2A (0.60) | MAPTALDH1A1HPGDKMT2AKDM4E | |
| SCHEMBL1176635 | 0.85 | MEN1 (0.69) | MAPTALDH1A1KMT2AKDM4EMEN1 | |
| Anthracene SCHEMBL29076817 | 0.84 | MEN1 (0.67) | MAPTALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL8549110 | 0.84 | RAB9A (0.62) | MAPTALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL3776520 | 0.82 | KMT2A (0.65) | MAPTALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL1122275 | 0.81 | HSD17B1 (0.76) | MAPTALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL11900180 | 0.81 | CASP6 (0.68) | MAPTALDH1A1HPGDKMT2AKDM4E | |
| SCHEMBL29963136 | 0.81 | HSD17B1 (0.76) | MAPTALDH1A1KMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040126892-A1 | Methods for characterizing a mixture of chemical compounds | ADVANCED CHEMISTRY DEVELOPMENT (CA) | 2004-07-01 | — | — | US | disclosed |