Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | BLM | P54132 | 1/20 | 0.65 |
| ▸ | AGER | Q15109 | 1/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinolinic Acid SCHEMBL14687247 | 0.82 | KDM4E (0.81) | KDM4EALDH1A1L3MBTL1ALOX15MAPT | |
| Phthalic Acid SCHEMBL321766 | 0.81 | ALDH1A1 (0.54) | KDM4EALDH1A1ALOX15MAPTTSHR | |
| Quinolinic Acid SCHEMBL69230 | 0.80 | KDM4E (1.00) | KDM4EALDH1A1L3MBTL1ALOX15MAPT | |
| Quinolinic Acid SCHEMBL29356188 | 0.80 | KDM4E (1.00) | KDM4EALDH1A1L3MBTL1ALOX15MAPT | |
| Quinolinic Acid SCHEMBL343618 | 0.80 | KDM4E (1.00) | KDM4EALDH1A1L3MBTL1ALOX15MAPT | |
| Quinolinic Acid SCHEMBL27676801 | 0.80 | KDM4E (1.00) | KDM4EALDH1A1L3MBTL1ALOX15MAPT | |
| Quinolinic Acid SCHEMBL29236531 | 0.80 | KDM4E (0.71) | KDM4EALDH1A1L3MBTL1ALOX15MAPT | |
| Quinolinic Acid SCHEMBL125075 | 0.79 | KDM4E (0.88) | KDM4EALDH1A1L3MBTL1ALOX15MAPT | |
| Quinolinic Acid SCHEMBL27862037 | 0.79 | KDM4E (0.88) | KDM4EALDH1A1L3MBTL1ALOX15MAPT | |
| Quinolinic Acid SCHEMBL5381551 | 0.79 | KDM4E (0.96) | KDM4EALDH1A1L3MBTL1ALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434965-B1 | Alkyl esters of 5-heterocyclic-pyridine-2,3-dicarboxylic acids and 5-heterocyclic 2-(2-imidazolin-2-yl) pyridines and methods for preparation thereof | AMERICAN CYANAMID CO (US) | 1998-05-20 | — | — | EP | claimed |
| US-5344935-A | Intermediates for herbicides | AMERICAN CYANAMID COMPANY (US) | 1994-09-06 | — | — | US | claimed |
| EP-0434965-A2 | Alkyl esters of 5-heterocyclic-pyridine-2,3-dicarboxylic acids and 5-heterocyclic 2-(2-imidazolin-2-yl) pyridines and methods for preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1991-07-03 | — | — | EP | claimed |