SCHEMBL8549284

SCHEMBL8549284

C/C=C/C=C/COC(=O)CCl

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 4/20 0.31
CNR1 P21554 2/20 0.31
PPARG P37231 1/20 0.31
PPARD Q03181 1/20 0.31
PPARA Q07869 1/20 0.31
SOAT1 P35610 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10779512 0.85
SCHEMBL10779518 0.85
SCHEMBL5837081 0.83 MGAM (0.41) CNR2CNR1PPARGPPARDPPARA
SCHEMBL3504118 0.82 NAAA (0.36) CNR2CNR1PPARGPPARDPPARA
SCHEMBL4216699 0.82 NAAA (0.36) CNR2CNR1PPARGPPARDPPARA
SCHEMBL4216701 0.82 NAAA (0.36) CNR2CNR1PPARGPPARDPPARA
SCHEMBL10718835 0.80 TSHR (0.33)
SCHEMBL10733049 0.80 TSHR (0.33)
SCHEMBL20646268 0.80 TSHR (0.46) SOAT1
SCHEMBL2146119 0.78 ALDH1A1 (0.41) CNR2CNR1PPARGPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0564924-B1 2-Oxoethyl derivatives as immunosuppressants BAYER AG (US) 1998-09-09 EP disclosed
US-5686424-A FOR TREATING INFLAMMATION MILES INC. (US) 1997-11-11 US disclosed
EP-0564924-A2 2-Oxoethyl derivatives as immunosuppressants Bayer Corporation (US) 1993-10-13 EP disclosed