Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PPIB | P23284 | 1/20 | 0.36 |
| ▸ | PPIA | P62937 | 1/20 | 0.36 |
| ▸ | PPID | Q08752 | 1/20 | 0.36 |
| ▸ | PPIG | Q13427 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542074 | 0.85 | KDM4E (0.42) | KMT2AMEN1KDM4EALDH1A1PKM | |
| SCHEMBL8545894 | 0.81 | CTSB (0.46) | KMT2AL3MBTL1KDM4EALDH1A1GAA | |
| SCHEMBL10699895 | 0.78 | CCR1 (0.54) | KMT2AL3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL8549278 | 0.75 | CHEK1 (0.36) | KMT2AMEN1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL8227659 | 0.68 | PPID (0.53) | KMT2AMEN1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL8672851 | 0.68 | NQO2 (0.43) | KDM4EALDH1A1HPGDCASP1CASP7 | |
| SCHEMBL391332 | 0.66 | GAA (0.65) | KMT2AALDH1A1HPGDHSD17B10TSHR | |
| Neocuproine SCHEMBL10556003 | 0.66 | CCR1 (0.56) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL12164701 | 0.66 | LMNA (0.47) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL29155843 | 0.65 | CCR1 (0.51) | L3MBTL1KDM4EALDH1A1HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0624097-B1 | TARGETING RADIOACTIVE IMMUNOREAGENTS | NYCOMED IMAGING AS (NO) | 1998-03-18 | — | — | EP | disclosed |
| US-5523402-A | COMPLEXING AGENTS FOR TARGETING RADIOACTIVE IMMUNOREAGENTS | STERLING WINTHROP INC. (US) | 1996-06-04 | — | — | US | disclosed |
| EP-0639083-A1 | COMPLEXING AGENTS AND TARGETING IMMUNOREAGENTS | NYCOMED IMAGING AS (NO) | 1995-02-22 | — | — | EP | disclosed |
| US-5367080-A | PYRIDINE DERIVATIVES | STERLING WINTHROP INC. (US) | 1994-11-22 | — | — | US | disclosed |
| WO-1993021957-A1 | COMPLEXING AGENTS AND TARGETING IMMUNOREAGENTS | STERLING WINTHROP INC. (US) | 1993-11-11 | — | — | WO | disclosed |