Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18253939 | 0.85 | KDM4E (0.56) | ALDH1A1MAPTKDM4ECA1L3MBTL1 | |
| SCHEMBL29169531 | 0.83 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL30825621 | 0.83 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL28864893 | 0.78 | ALDH1A1 (0.53) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL6981306 | 0.77 | ALDH1A1 (0.43) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL12405340 | 0.76 | SLC18A2 (0.51) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL10378250 | 0.75 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL182214 | 0.74 | KDM4E (0.59) | ALDH1A1MAPTKDM4EHPGDNPC1 | |
| SCHEMBL8546560 | 0.74 | ALDH1A1 (0.42) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL18253935 | 0.73 | KDM4E (0.53) | ALDH1A1KDM4EKMT2ACA1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821674-A1 | CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | G.D. SEARLE & CO. (US) | 1998-02-04 | — | — | EP | disclosed |
| US-3989714-A | ANTIVIRAL | WARNER-LAMBERT COMPANY (US) | 1976-11-02 | — | — | US | disclosed |