Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | RXRA | P19793 | 3/20 | 0.51 |
| ▸ | RXRB | P28702 | 3/20 | 0.51 |
| ▸ | RXRG | P48443 | 3/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 10/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.50 |
| ▸ | CA1 | P00915 | 5/20 | 0.46 |
| ▸ | CA2 | P00918 | 5/20 | 0.46 |
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | CA4 | P22748 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6026434 | 0.88 | PTGS2 (0.55) | MAOAMAOBRXRARXRBRXRG | |
| SCHEMBL7501616 | 0.88 | PTGS2 (0.55) | MAOAMAOBRXRARXRBRXRG | |
| SCHEMBL7508637 | 0.87 | PTGS2 (0.67) | MAOAMAOBPTGS2PTGS1CA1 | |
| SCHEMBL5732336 | 0.86 | NR4A2 (0.60) | MAOAMAOBRXRARXRBRXRG | |
| SCHEMBL5733069 | 0.86 | NR4A2 (0.60) | MAOAMAOBRXRARXRBRXRG | |
| SCHEMBL6308845 | 0.84 | RXRA (0.49) | MAOAMAOBRXRARXRBRXRG | |
| SCHEMBL6310934 | 0.84 | RXRA (0.49) | MAOAMAOBRXRARXRBRXRG | |
| SCHEMBL8547060 | 0.84 | PTGS2 (0.50) | MAOAMAOBRXRARXRBRXRG | |
| SCHEMBL8552170 | 0.84 | PTGS2 (0.50) | MAOAMAOBRXRARXRBRXRG | |
| SCHEMBL7504153 | 0.83 | RXRA (0.53) | MAOAMAOBRXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825989-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-03-04 | — | — | EP | claimed |
| WO-1996036617-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-11-21 | — | — | WO | claimed |