Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 19/20 | 0.45 |
| ▸ | ITGAV | P06756 | 17/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.44 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7406830 | 0.83 | ITGB3 (0.66) | ITGB3ITGAVITGA2B | |
| SCHEMBL7980601 | 0.81 | ITGB3 (0.67) | ITGB3ITGAVITGA2B | |
| SCHEMBL7401937 | 0.75 | ITGB3 (0.51) | ITGB3ITGAVITGA2B | |
| SCHEMBL7347923 | 0.75 | ITGB3 (0.67) | ITGB3ITGAVITGA2B | |
| SCHEMBL8646899 | 0.74 | ITGB3 (0.43) | ITGB3ITGAVITGA2BMALT1 | |
| SCHEMBL8646936 | 0.73 | ITGB3 (0.42) | ITGB3ITGAVITGA2BMALT1 | |
| SCHEMBL7405908 | 0.70 | ITGB3 (0.51) | ITGB3ITGAVITGA2B | |
| SCHEMBL8647489 | 0.70 | ITGB3 (0.43) | ITGB3ITGAVITGA2BMALT1 | |
| SCHEMBL7347802 | 0.69 | ITGB3 (0.38) | ITGB3ITGAVITGA2B | |
| SCHEMBL8643354 | 0.69 | ITGB3 (0.42) | ITGB3ITGAVITGA2BMALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828737-A1 | ISOXAZOLINE AND ISOXAZOLE DERIVATIVES AS INTEGRIN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-03-18 | — | — | EP | disclosed |