Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 13/20 | 0.43 |
| ▸ | ITGAV | P06756 | 12/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.36 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8646936 | 0.85 | ITGB3 (0.42) | ITGB3ITGAVMALT1ITGA2BCXCR4 | |
| SCHEMBL8646899 | 0.84 | ITGB3 (0.43) | ITGB3ITGAVMALT1ITGA2BCXCR4 | |
| SCHEMBL8646093 | 0.83 | ITGB3 (0.40) | ITGB3ITGAVITGA2BTGM2 | |
| SCHEMBL8647492 | 0.82 | ITGB3 (0.44) | ITGB3ITGAVMALT1ITGA2BCXCR4 | |
| SCHEMBL8646125 | 0.80 | ITGB3 (0.36) | ITGB3ITGAVITGA2BTGM2 | |
| SCHEMBL8643354 | 0.80 | ITGB3 (0.42) | ITGB3ITGAVMALT1ITGA2BCXCR4 | |
| SCHEMBL8644171 | 0.79 | ITGB3 (0.46) | ITGB3ITGAVMALT1ITGA2BITGB5 | |
| SCHEMBL8648458 | 0.79 | ITGB3 (0.36) | ITGB3ITGAVITGA2BTGM2 | |
| SCHEMBL8682244 | 0.77 | ITGB3 (0.46) | ITGB3ITGAVMALT1ITGA2BCXCR4 | |
| Hydrochloric Acid SCHEMBL8682425 | 0.76 | ITGB3 (0.48) | ITGB3ITGAVMALT1ITGA2BCXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710159-A | IMIDAZOLIN-2-YLAMINOPROPOXY)ISOXAZOL-5-CARBONYLAMINO-2 -BENZYLOXYCARBONYLAMINOPROPIONIC ACID AS ANTIINFLAMMATORY AGENTS, BONE DEGRADATION, TUMORS, METASTASES AND THROMBOSIS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-01-20 | — | — | US | claimed |
| US-5710159-A | IMIDAZOLIN-2-YLAMINOPROPOXY)ISOXAZOL-5-CARBONYLAMINO-2 -BENZYLOXYCARBONYLAMINOPROPIONIC ACID AS ANTIINFLAMMATORY AGENTS, BONE DEGRADATION, TUMORS, METASTASES AND THROMBOSIS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-01-20 | — | — | US | disclosed |