Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2141946 | 1.00 | LMNA (0.61) | LMNAMAPK1MAPTGAAALDH1A1 | |
| SCHEMBL12310782 | 0.86 | LMNA (0.61) | LMNAMAPK1MAPTGAAALDH1A1 | |
| SCHEMBL8155147 | 0.85 | ANPEP (0.57) | MAPTGAAALDH1A1CYP3A4KMT2A | |
| SCHEMBL4746610 | 0.85 | ANPEP (0.57) | MAPTGAAALDH1A1CYP3A4KMT2A | |
| SCHEMBL7432155 | 0.85 | ANPEP (0.57) | MAPTGAAALDH1A1CYP3A4KMT2A | |
| Hydrochloric Acid SCHEMBL7328710 | 0.85 | LMNA (0.60) | LMNAMAPK1MAPTGAAALDH1A1 | |
| SCHEMBL3668459 | 0.84 | CA1 (0.47) | KMT2ATERT | |
| SCHEMBL4747242 | 0.84 | MEN1 (0.56) | GAAALDH1A1POLBPKMKMT2A | |
| Hydrochloric Acid SCHEMBL8617714 | 0.84 | ANPEP (0.56) | MAPTGAAALDH1A1CYP3A4KMT2A | |
| Hydrochloric Acid SCHEMBL8617723 | 0.84 | ANPEP (0.56) | MAPTGAAALDH1A1CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |
| US-5686424-A | FOR TREATING INFLAMMATION | MILES INC. (US) | 1997-11-11 | — | — | US | disclosed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | disclosed |