Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 12/20 | 0.97 |
| ▸ | THRB | P10828 | 12/20 | 0.97 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.62 |
| ▸ | RARB | P10826 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | RARA | P10276 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | MTOR | P42345 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11664808 | 0.98 | THRA (1.00) | THRATHRBHAO1RARBMEN1 | |
| SCHEMBL11380651 | 0.98 | THRA (1.00) | THRATHRBHAO1RARBMEN1 | |
| SCHEMBL9331746 | 0.95 | THRA (0.87) | THRATHRBHAO1RARBALDH1A1 | |
| SCHEMBL12064925 | 0.90 | THRA (0.79) | THRATHRBHAO1RARBALDH1A1 | |
| SCHEMBL11851271 | 0.87 | THRB (0.74) | THRATHRBHAO1KMT2AALDH1A1 | |
| SCHEMBL12064924 | 0.86 | THRA (0.73) | THRATHRBHAO1RARBALDH1A1 | |
| SCHEMBL12064834 | 0.86 | THRA (0.73) | THRATHRBHAO1MEN1KMT2A | |
| SCHEMBL14555309 | 0.85 | THRA (0.72) | THRATHRBHAO1RARBALDH1A1 | |
| SCHEMBL14555314 | 0.85 | THRB (0.72) | THRATHRBHAO1RARBALDH1A1 | |
| SCHEMBL7137148 | 0.85 | THRA (0.72) | THRATHRBHAO1RARBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |
| US-5686424-A | FOR TREATING INFLAMMATION | MILES INC. (US) | 1997-11-11 | — | — | US | disclosed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | disclosed |