Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | AGER | Q15109 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.31 |
| ▸ | ASPH | Q12797 | 3/20 | 0.31 |
| ▸ | KDM8 | Q8N371 | 3/20 | 0.31 |
| ▸ | DHODH | Q02127 | 2/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544532 | 0.74 | KDM4E (0.40) | KDM4EALDH1A1L3MBTL1CYP3A4MAPT | |
| SCHEMBL10586417 | 0.74 | KDM4E (0.54) | KDM4EALDH1A1L3MBTL1CYP3A4MAPT | |
| SCHEMBL8545598 | 0.72 | KDM4E (0.38) | KDM4EALDH1A1L3MBTL1CYP3A4MAPT | |
| SCHEMBL8544867 | 0.72 | KDM4E (0.38) | KDM4EALDH1A1L3MBTL1CYP3A4MAPT | |
| SCHEMBL19857468 | 0.70 | GABRP (0.44) | KDM4EALDH1A1L3MBTL1CYP3A4MAPT | |
| SCHEMBL1171022 | 0.67 | KDM4E (0.45) | KDM4EALDH1A1L3MBTL1CYP3A4MAPT | |
| SCHEMBL19857472 | 0.67 | KDM4E (0.45) | KDM4EALDH1A1L3MBTL1CYP3A4MAPT | |
| SCHEMBL8542111 | 0.66 | POLB (0.42) | KDM4EALDH1A1L3MBTL1CYP3A4MAPT | |
| SCHEMBL1819716 | 0.66 | GABRP (0.44) | KDM4EALDH1A1L3MBTL1CYP3A4MAPT | |
| SCHEMBL617721 | 0.66 | KDM4E (0.44) | KDM4EALDH1A1L3MBTL1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434965-B1 | Alkyl esters of 5-heterocyclic-pyridine-2,3-dicarboxylic acids and 5-heterocyclic 2-(2-imidazolin-2-yl) pyridines and methods for preparation thereof | AMERICAN CYANAMID CO (US) | 1998-05-20 | — | — | EP | disclosed |
| US-5405827-A | 5-heterocyclic 2-(2-imidazolin-2-yl)pyridines, useful as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1995-04-11 | — | — | US | disclosed |
| US-5344935-A | Intermediates for herbicides | AMERICAN CYANAMID COMPANY (US) | 1994-09-06 | — | — | US | disclosed |
| US-5283230-A | Pre- and post-emergence herbicides | AMERICAN CYANAMID COMPANY (US) | 1994-02-01 | — | — | US | disclosed |
| US-5225564-A | Acetalization, amination or sulfiding in a solvent | AMERICAN CYANAMID COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| US-5039333-A | 5-heterocyclic 2-(2-imidazolin-2-yl)pyridines, useful as herbicidal agents | AMERICAN CYANAMID COMPANY | 1991-08-13 | — | — | US | disclosed |
| EP-0434965-A2 | Alkyl esters of 5-heterocyclic-pyridine-2,3-dicarboxylic acids and 5-heterocyclic 2-(2-imidazolin-2-yl) pyridines and methods for preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1991-07-03 | — | — | EP | disclosed |
| US-5026859-A | Intermediates for herbicides | AMERICAN CYANAMID COMPANY (US) | 1991-06-25 | — | — | US | disclosed |