Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | AGER | Q15109 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.33 |
| ▸ | ASPH | Q12797 | 1/20 | 0.32 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545598 | 0.97 | KDM4E (0.38) | KDM4EL3MBTL1TSHRALDH1A1CYP3A4 | |
| SCHEMBL8544532 | 0.94 | KDM4E (0.40) | KDM4EL3MBTL1TSHRALDH1A1CYP3A4 | |
| SCHEMBL20489642 | 0.84 | ALDH1A1 (0.35) | KDM4EL3MBTL1ALDH1A1SMN1; SMN2HCAR3 | |
| SCHEMBL8542228 | 0.82 | — | — | |
| SCHEMBL9724759 | 0.80 | SMN1; SMN2 (0.35) | KDM4EL3MBTL1ALDH1A1ALOX15NPSR1 | |
| SCHEMBL8542643 | 0.77 | KDM4E (0.38) | KDM4EALDH1A1SMN1; SMN2HTTHSD17B10 | |
| SCHEMBL10586417 | 0.75 | KDM4E (0.54) | KDM4EL3MBTL1TSHRALDH1A1CYP3A4 | |
| SCHEMBL8546459 | 0.74 | KDM4E (0.38) | KDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL8549567 | 0.72 | KDM4E (0.40) | KDM4EL3MBTL1TSHRALDH1A1CYP3A4 | |
| SCHEMBL26717114 | 0.71 | ACMSD (0.40) | KDM4ETSHRALDH1A1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434965-B1 | Alkyl esters of 5-heterocyclic-pyridine-2,3-dicarboxylic acids and 5-heterocyclic 2-(2-imidazolin-2-yl) pyridines and methods for preparation thereof | AMERICAN CYANAMID CO (US) | 1998-05-20 | — | — | EP | claimed |