SCHEMBL8549832

SCHEMBL8549832

C=CC(NC(C=C)C(=O)O)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
BLM P54132 1/20 0.31
SLC6A3 Q01959 1/20 0.31
MEN1 O00255 1/20 0.31
CYP2D6 P10635 1/20 0.31
TSHR P16473 1/20 0.31
NFKB1 P19838 1/20 0.31
CYP2C19 P33261 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5691836 1.00 LMNA (0.35) LMNASLC6A2SLC6A4BLMSLC6A3
SCHEMBL9523796 0.83 TSHR (0.33) TSHR
SCHEMBL15869968 0.78
SCHEMBL8815046 0.78 FOLH1 (0.33) LMNAMEN1TSHRKMT2A
SCHEMBL12598425 0.78
SCHEMBL9410682 0.78 KDM4E (0.44) BLMNFKB1
SCHEMBL3312141 0.78 TSHR (0.33) SLC6A2SLC6A4BLMSLC6A3MEN1
SCHEMBL18685964 0.76 MME (0.33)
SCHEMBL7142379 0.76
SCHEMBL6050157 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11148089-A None JP disclosed
JP-H11148089-A LIQUID DETERGENT COMPOSITION LION CORP 1999-06-02 JP disclosed
EP-0383536-A2 Thermo-sensitive transfer printing medium SEIKO INSTRUMENTS INC. (JP) 1990-08-22 EP disclosed