SCHEMBL7142379

SCHEMBL7142379

C=CC(NC=O)C(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1194187 0.80
SCHEMBL11160571 0.79
SCHEMBL11160570 0.79
SCHEMBL16296905 0.78
Imidazole SCHEMBL1162458 0.78 ALDH1A1 (0.39)
SCHEMBL8549832 0.76 LMNA (0.35)
SCHEMBL5691836 0.76 LMNA (0.35)
SCHEMBL20365692 0.75 SMN1; SMN2 (0.34)
SCHEMBL8815046 0.72 FOLH1 (0.33)
SCHEMBL12598425 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6361777-B1 COVALENTLY COUPLING POLYSACCHARIDE TO BIOPOLYMER HAVING HYDROXYL, AMINO AND/OR MERCAPTO GROUPS BY ACTIVATING POLYSACCHARIDE WITH CYANOGEN BROMIDE, THIOLATING WITH AMINOTHIOL LINKER, REACTING WITH BIOPOLYMER DE STAAT DER NEDERLANDEN,VERTEGENWOORDIGD DOOR DE MINISTER VAN WELZIJN, VOLKSGEZONDHEID EN CULTUUR (NL) 2002-03-26 US claimed
EP-0848011-B1 Method of coupling polysaccharides to proteins NEDERLANDEN STAAT (NL) 2001-03-21 EP claimed
WO-1998027107-A1 METHOD OF COUPLING POLYSACCHARIDES TO PROTEINS DE STAAT DER NEDERLANDEN, VERTEGENWOORDIGD DOOR DE MINISTER VAN WELZIJN, VOLKSGEZONDHEID EN CULTUUR (NL) 1998-06-25 WO claimed
EP-0848011-A1 Method of coupling polysaccharides to proteins DE STAAT DER NEDERLANDEN VERTEGENWOORDIGD DOOR DE MINISTER VAN WELZIJN, VOLKSGEZONDHEID EN CULTUUR (NL) 1998-06-17 EP claimed
CN-103100312-B Preparation method of amino-containing copolymer film separating acidic gas UNIV XI AN JIAOTONG 2015-01-07 CN disclosed
CN-103100312-A Preparation method of amino-containing copolymer film separating acidic gas UNIV XI AN JIAOTONG 2013-05-15 CN disclosed
WO-2003080060-A1 SUBSTITUTED PIPERAZINE ANTITHROMBOTIC PAI-1 INHIBITORS SCHERING AKTIENGESELLSCHAFT (DE) 2003-10-02 WO disclosed
US-6361777-B1 COVALENTLY COUPLING POLYSACCHARIDE TO BIOPOLYMER HAVING HYDROXYL, AMINO AND/OR MERCAPTO GROUPS BY ACTIVATING POLYSACCHARIDE WITH CYANOGEN BROMIDE, THIOLATING WITH AMINOTHIOL LINKER, REACTING WITH BIOPOLYMER DE STAAT DER NEDERLANDEN,VERTEGENWOORDIGD DOOR DE MINISTER VAN WELZIJN, VOLKSGEZONDHEID EN CULTUUR (NL) 2002-03-26 US disclosed
US-6361777-B1 COVALENTLY COUPLING POLYSACCHARIDE TO BIOPOLYMER HAVING HYDROXYL, AMINO AND/OR MERCAPTO GROUPS BY ACTIVATING POLYSACCHARIDE WITH CYANOGEN BROMIDE, THIOLATING WITH AMINOTHIOL LINKER, REACTING WITH BIOPOLYMER DE STAAT DER NEDERLANDEN,VERTEGENWOORDIGD DOOR DE MINISTER VAN WELZIJN, VOLKSGEZONDHEID EN CULTUUR (NL) 2002-03-26 US disclosed
WO-1998027107-A8 METHOD OF COUPLING POLYSACCHARIDES TO PROTEINS NEDERLANDEN STAAT (NL) 2000-01-20 WO disclosed
WO-1998027107-A1 METHOD OF COUPLING POLYSACCHARIDES TO PROTEINS DE STAAT DER NEDERLANDEN, VERTEGENWOORDIGD DOOR DE MINISTER VAN WELZIJN, VOLKSGEZONDHEID EN CULTUUR (NL) 1998-06-25 WO disclosed
EP-0848011-A1 Method of coupling polysaccharides to proteins DE STAAT DER NEDERLANDEN VERTEGENWOORDIGD DOOR DE MINISTER VAN WELZIJN, VOLKSGEZONDHEID EN CULTUUR (NL) 1998-06-17 EP disclosed