Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550068 | 1.00 | ALDH1A1 (0.37) | ALDH1A1MAPTTSHR | |
| SCHEMBL11680445 | 0.70 | — | — | |
| SCHEMBL11680446 | 0.70 | — | — | |
| SCHEMBL2735553 | 0.65 | ALDH1A1 (0.50) | ALDH1A1MAPT | |
| SCHEMBL15727980 | 0.65 | ALDH1A1 (0.34) | ALDH1A1MAPT | |
| SCHEMBL7555797 | 0.65 | ALDH1A1 (0.50) | ALDH1A1MAPT | |
| SCHEMBL17135973 | 0.65 | ALDH1A1 (0.50) | ALDH1A1MAPT | |
| SCHEMBL11237755 | 0.64 | ALDH1A1 (0.49) | ALDH1A1MAPT | |
| SCHEMBL11237751 | 0.64 | ALDH1A1 (0.49) | ALDH1A1MAPT | |
| SCHEMBL21247206 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0824523-A1 | NITRIC OXIDE SYNTHASE INHIBITORS DERIVED FROM CYCLIC AMIDINES | G.D. Searle & Co. (US) | 1998-02-25 | — | — | EP | disclosed |
| WO-1996035677-A1 | NITRIC OXIDE SYNTHASE INHIBITORS DERIVED FROM CYCLIC AMIDINES | G.D. SEARLE & CO. (US) | 1996-11-14 | — | — | WO | disclosed |