SCHEMBL8550123

SCHEMBL8550123

CC(C)N(C(=O)n1nnn(CC=O)c1=O)c1ccc(Cl)cc1

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GPBAR1 Q8TDU6 2/20 0.34
ALDH1A1 P00352 2/20 0.33
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
KCNK3 O14649 1/20 0.32
KCNK9 Q9NPC2 1/20 0.32
MAPKAPK2 P49137 1/20 0.31
LIPE Q05469 1/20 0.31
USP2 O75604 1/20 0.31
CHRNB2 P17787 1/20 0.30
CHRNB4 P30926 1/20 0.30
CHRNA3 P32297 1/20 0.30
CHRNA4 P43681 1/20 0.30
HTR2C P28335 1/20 0.30
P2RX3 P56373 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8545512 0.89 TRPM8 (0.36) ALDH1A1LMNATP53SMN1; SMN2
SCHEMBL8551886 0.88 MC4R (0.32) ALDH1A1LMNATP53SMN1; SMN2
SCHEMBL8550504 0.88 ALDH1A1 (0.43) ALDH1A1LMNATP53SMN1; SMN2
SCHEMBL8546323 0.84 GPBAR1 (0.34) GPBAR1ALDH1A1LMNATP53SMN1; SMN2
SCHEMBL8551340 0.82 GPBAR1 (0.33) GPBAR1ALDH1A1LMNATP53SMN1; SMN2
SCHEMBL8551702 0.81 ALDH1A1 (0.34) GPBAR1ALDH1A1LMNATP53SMN1; SMN2
SCHEMBL7977970 0.77 ALDH1A1 (0.42) ALDH1A1LMNATP53SMN1; SMN2
SCHEMBL9620371 0.74 ALDH1A1 (0.46) ALDH1A1LMNATP53SMN1; SMN2
SCHEMBL8690403 0.73 ALDH1A1 (0.49) ALDH1A1LMNATP53SMN1; SMN2HTR2C
SCHEMBL8551629 0.73 TRPM8 (0.34) ALDH1A1LMNATP53SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0820994-A1 Tetrazolinones as herbicides and intermediates NIHON BAYER AGROCHEM K.K. (JP) 1998-01-28 EP disclosed