Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 11/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550157 | 1.00 | TDP1 (0.50) | TDP1CTSKPPARAPPARGCTSS | |
| SCHEMBL8613012 | 1.00 | TDP1 (0.50) | TDP1CTSKPPARAPPARGCTSS | |
| SCHEMBL8550164 | 1.00 | TDP1 (0.50) | TDP1CTSKPPARAPPARGCTSS | |
| SCHEMBL8136411 | 0.89 | CTSK (0.46) | TDP1CTSKPPARAPPARGCTSS | |
| SCHEMBL8136416 | 0.89 | CTSK (0.46) | TDP1CTSKPPARAPPARGCTSS | |
| SCHEMBL13986003 | 0.82 | TDP1 (0.47) | TDP1CTSKPPARAPPARGCTSS | |
| SCHEMBL10980321 | 0.81 | PPARA (0.47) | TDP1CTSKPPARAPPARGCTSS | |
| SCHEMBL9058208 | 0.81 | PPARA (0.47) | TDP1CTSKPPARAPPARGCTSS | |
| SCHEMBL10973888 | 0.81 | PPARA (0.47) | TDP1CTSKPPARAPPARGCTSS | |
| SCHEMBL13986019 | 0.80 | TDP1 (0.45) | TDP1CTSKPPARAPPARGCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |
| EP-0610745-A2 | Novel aminomethylene derivatives as immunosuppressants | Bayer Corporation (US) | 1994-08-17 | — | — | EP | disclosed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | disclosed |