Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.47 |
| ▸ | PPARG | P37231 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 5/20 | 0.44 |
| ▸ | CTSS | P25774 | 3/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9058208 | 1.00 | PPARA (0.47) | PPARAPPARGTDP1ATMCTSK | |
| SCHEMBL10973888 | 1.00 | PPARA (0.47) | PPARAPPARGTDP1ATMCTSK | |
| SCHEMBL9059145 | 0.83 | PPARA (0.47) | PPARAPPARG | |
| SCHEMBL8550161 | 0.81 | TDP1 (0.50) | PPARAPPARGTDP1ATMCTSK | |
| SCHEMBL8550157 | 0.81 | TDP1 (0.50) | PPARAPPARGTDP1ATMCTSK | |
| SCHEMBL8613012 | 0.81 | TDP1 (0.50) | PPARAPPARGTDP1ATMCTSK | |
| SCHEMBL8550164 | 0.81 | TDP1 (0.50) | PPARAPPARGTDP1ATMCTSK | |
| SCHEMBL10771726 | 0.81 | CTSL (0.41) | PPARAPPARGATMCTSKCTSS | |
| SCHEMBL10771722 | 0.81 | CTSL (0.41) | PPARAPPARGATMCTSKCTSS | |
| SCHEMBL8349897 | 0.80 | CTSK (0.52) | PPARAPPARGATMCTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4533657-A | Analgesic dipeptide amides and method of use and composition thereof | STERLING DRUG INC. (US) | 1985-08-06 | — | — | US | disclosed |