Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.45 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2022437 | 0.82 | ALDH1A1 (0.41) | GRM5KDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL8304003 | 0.78 | DAO (0.50) | GRM5KDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL8547639 | 0.78 | FFAR1 (0.39) | GRM5KDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL8549621 | 0.75 | FFAR1 (0.54) | GRM5KDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL8550218 | 0.75 | FFAR1 (0.40) | GRM5KDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL8547642 | 0.74 | FFAR1 (0.39) | GRM5KDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL8551167 | 0.74 | FFAR1 (0.53) | KDM4EMEN1ALDH1A1KMT2AFFAR1 | |
| SCHEMBL8547496 | 0.74 | FFAR1 (0.53) | KDM4EMEN1ALDH1A1KMT2AFFAR1 | |
| SCHEMBL5430787 | 0.73 | DAO (0.42) | GRM5KDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL8545736 | 0.73 | FFAR1 (0.53) | ALDH1A1FFAR1PLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |