Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.41 |
| ▸ | ALPL | P05186 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL877436 | 0.81 | HCAR2 (0.52) | HCAR2DAOCCNA2CDK2CCNA1 | |
| SCHEMBL13807631 | 0.81 | PDE3B (0.43) | HCAR2DAOCCNA2CDK2CCNA1 | |
| Hydrochloric Acid SCHEMBL1371875 | 0.79 | HCAR2 (0.50) | HCAR2DAOCCNA2CDK2CCNA1 | |
| Succinic Acid SCHEMBL30364361 | 0.77 | HCAR2 (0.52) | HCAR2DAONPSR1NR1H4CCNA2 | |
| SCHEMBL14971487 | 0.75 | ALDH1A1 (0.42) | NPSR1NR1H4ALDH1A1 | |
| SCHEMBL14261205 | 0.74 | — | — | |
| SCHEMBL18534204 | 0.74 | CYTH3 (0.53) | NPSR1NR1H4CHRM1APEX1ALDH1A1 | |
| SCHEMBL12174907 | 0.73 | HCAR2 (0.47) | HCAR2DAOCCNA2CDK2CCNA1 | |
| SCHEMBL8720555 | 0.72 | — | — | |
| SCHEMBL5336589 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114152706-A | Method for simultaneously detecting various newborn screening metabolites in dried blood slices | 上海义准生物有限公司 | 2022-03-08 | — | — | CN | claimed |
| EP-2155185-B2 | DETECTING SUCCINYLACETONE | PERKINELMER HEALTH SCI INC (US) | 2021-12-01 | — | — | EP | claimed |
| US-8513025-B2 | Detecting succinylacetone | PERKINELMER HEALTH SCIENCES, INC. (US) | 2013-08-20 | — | — | US | claimed |
| US-20120309096-A1 | DETECTING SUCCINYLACETONE | PERKINELMER HEALTH SCIENCES, INC. (US) | 2012-12-06 | — | — | US | claimed |
| US-8278116-B2 | Detecting succinylacetone | PERKINELMER HEALTH SCIENCES, INC. (US) | 2012-10-02 | — | — | US | claimed |
| EP-2155185-B1 | DETECTING SUCCINYLACETONE | PERKINELMER HEALTH SCI INC (US) | 2012-03-28 | — | — | EP | claimed |
| US-20110201539-A1 | DETECTING SUCCINYLACETONE | PERKINELMER HEALTH SCIENCES, INC. (US) | 2011-08-18 | — | — | US | claimed |
| US-7951608-B2 | Detecting succinylacetone | PERKINELMER HEALTH SCIENCES, INC. (US) | 2011-05-31 | — | — | US | claimed |
| CN-114152706-A | Method for simultaneously detecting various newborn screening metabolites in dried blood slices | 上海义准生物有限公司 | 2022-03-08 | — | — | CN | disclosed |
| EP-2155185-B2 | DETECTING SUCCINYLACETONE | PERKINELMER HEALTH SCI INC (US) | 2021-12-01 | — | — | EP | disclosed |
| US-8513025-B2 | Detecting succinylacetone | PERKINELMER HEALTH SCIENCES, INC. (US) | 2013-08-20 | — | — | US | disclosed |
| US-20120309096-A1 | DETECTING SUCCINYLACETONE | PERKINELMER HEALTH SCIENCES, INC. (US) | 2012-12-06 | — | — | US | disclosed |
| US-8278116-B2 | Detecting succinylacetone | PERKINELMER HEALTH SCIENCES, INC. (US) | 2012-10-02 | — | — | US | disclosed |
| EP-2155185-B1 | DETECTING SUCCINYLACETONE | PERKINELMER HEALTH SCI INC (US) | 2012-03-28 | — | — | EP | disclosed |
| US-20110201539-A1 | DETECTING SUCCINYLACETONE | PERKINELMER HEALTH SCIENCES, INC. (US) | 2011-08-18 | — | — | US | disclosed |
| US-7951608-B2 | Detecting succinylacetone | PERKINELMER HEALTH SCIENCES, INC. (US) | 2011-05-31 | — | — | US | disclosed |
| EP-2155185-A1 | DETECTING SUCCINYLACETONE | Perkinelmer Health Sciences, Inc. (US) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008137868-A1 | DETECTING SUCCINYLACETONE | PERKINELMER LAS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |
| US-20080274563-A1 | DETECTING SUCCINYLACETONE | PERKINELMER LAS, INC. (US) | 2008-11-06 | — | — | US | disclosed |