Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYTH3 | O43739 | 1/20 | 0.53 |
| ▸ | BTK | Q06187 | 1/20 | 0.53 |
| ▸ | EPN1 | Q9Y6I3 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.32 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.32 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.32 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL855024 | 0.74 | HCAR2 (0.48) | ALDH1A1NR1H4NPSR1CHRM1APEX1 | |
| SCHEMBL16561806 | 0.73 | CYTH3 (0.49) | CYTH3BTKEPN1ALDH1A1NR1H4 | |
| SCHEMBL14971487 | 0.71 | ALDH1A1 (0.42) | ALDH1A1NR1H4NPSR1 | |
| SCHEMBL18571023 | 0.68 | NR1H4 (0.36) | ALDH1A1NR1H4NPSR1 | |
| SCHEMBL5678779 | 0.67 | ALDH1A1 (0.41) | ALDH1A1FFAR1NR1H4KEAP1 | |
| SCHEMBL18534222 | 0.67 | CHRM1 (0.43) | CYTH3BTKEPN1ALDH1A1CHRM1 | |
| SCHEMBL29213733 | 0.62 | FFAR1 (0.59) | FFAR1KEAP1L3MBTL1 | |
| SCHEMBL7697974 | 0.62 | KEAP1 (0.42) | ALDH1A1FFAR1CHRM1KEAP1HDAC6 | |
| SCHEMBL2113281 | 0.61 | FFAR1 (0.53) | FFAR1NPSR1KEAP1 | |
| Bromide SCHEMBL28900199 | 0.61 | KEAP1 (0.41) | ALDH1A1FFAR1CHRM1KEAP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2976346-B1 | PHOSPHOHISTIDINE AND PHOSPHOTYROSINE ANALOGUES | UNIV SHEFFIELD (GB) | 2017-02-22 | — | — | EP | disclosed |