Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 6/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 6/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.51 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.51 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.51 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.51 |
| ▸ | CHRNG | P07510 | 1/20 | 0.51 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.51 |
| ▸ | CHRND | Q07001 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7413429 | 0.99 | CHRNB2 (0.50) | CHRNB2CHRNA4CHRNA7CHRNA3CHRNB4 | |
| SCHEMBL3942452 | 0.79 | CHRNA3 (0.81) | CHRNB2CHRNA4CHRNA7CHRNA3CHRNB4 | |
| SCHEMBL905201 | 0.79 | CHRNA3 (0.81) | CHRNB2CHRNA4CHRNA7CHRNA3CHRNB4 | |
| SCHEMBL905236 | 0.79 | CHRNA3 (0.81) | CHRNB2CHRNA4CHRNA7CHRNA3CHRNB4 | |
| Hydrochloric Acid SCHEMBL7840031 | 0.78 | CHRNA3 (0.78) | CHRNB2CHRNA4CHRNA7CHRNA3CHRNB4 | |
| Hydrochloric Acid SCHEMBL8439827 | 0.78 | CHRNA3 (0.78) | CHRNB2CHRNA4CHRNA7CHRNA3CHRNB4 | |
| SCHEMBL8438067 | 0.77 | CHRNA3 (0.67) | CHRNB2CHRNA4CHRNA7CHRNA3CHRNB4 | |
| SCHEMBL8436385 | 0.77 | CHRNB2 (0.59) | CHRNB2CHRNA4CHRNA7CHRNA3CHRNB4 | |
| Hydrochloric Acid SCHEMBL7410981 | 0.76 | CHRNB2 (0.58) | CHRNB2CHRNA4CHRNA7CHRNA3CHRNB4 | |
| SCHEMBL24154367 | 0.75 | CHRNA3 (0.78) | CHRNB2CHRNA4CHRNA7CHRNA3CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846114-A1 | 3-PYRIDYLOXYALKYL HETEROCYCLIC ETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | Abbott Laboratories (US) | 1998-06-10 | — | — | EP | claimed |
| WO-1996040682-A1 | 3-PYRIDYLOXYALKYL HETEROCYCLIC ETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | ABBOTT LABORATORIES (US) | 1996-12-19 | — | — | WO | claimed |