Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.30 |
| ▸ | QPCT | Q16769 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551217 | 0.90 | GNRHR (0.37) | GNRHRKDM4ESMN1; SMN2NPY5RQPCT | |
| SCHEMBL8552137 | 0.81 | GNRHR (0.34) | GNRHRKMT2AKDM4ESMN1; SMN2NPY5R | |
| SCHEMBL7144826 | 0.81 | MAPT (0.45) | GNRHRKMT2AKDM4ESMN1; SMN2 | |
| Malonic Acid SCHEMBL8552650 | 0.76 | SMN1; SMN2 (0.34) | KDM4ESMN1; SMN2 | |
| SCHEMBL8549069 | 0.72 | GNRHR (0.38) | GNRHRKMT2AKDM4ESMN1; SMN2NPY5R | |
| SCHEMBL7145976 | 0.71 | GNRHR (0.48) | GNRHRKMT2ASMN1; SMN2 | |
| SCHEMBL8551891 | 0.69 | HTR1F (0.49) | KDM4ESMN1; SMN2 | |
| SCHEMBL4001727 | 0.62 | KDM4E (0.47) | KDM4ESMN1; SMN2 | |
| SCHEMBL6430952 | 0.61 | SIGMAR1 (0.49) | KDM4ESMN1; SMN2 | |
| SCHEMBL7014859 | 0.61 | NPY5R (0.38) | KMT2AKDM4ESMN1; SMN2NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |