Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548671 | 0.76 | LMNA (0.51) | ALDH1A1KDM4ETDP1SMN1; SMN2LMNA | |
| SCHEMBL12484518 | 0.73 | TNFRSF1A (1.00) | TNFRSF1AABCB1ABCG2TUBB4ATUBB | |
| SCHEMBL12484514 | 0.73 | TNFRSF1A (1.00) | TNFRSF1AABCB1ABCG2TUBB4ATUBB | |
| Dimethylamine SCHEMBL6356653 | 0.72 | TNFRSF1A (0.92) | TNFRSF1AALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL8545816 | 0.70 | KMT2A (0.46) | TNFRSF1AALDH1A1KDM4ESMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL8550542 | 0.69 | ALDH1A1 (0.45) | TNFRSF1AALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL10882250 | 0.68 | KMT2A (0.64) | ALDH1A1KDM4EMEN1KMT2ATUBB4A | |
| SCHEMBL7046987 | 0.68 | ALDH1A1 (0.72) | ALDH1A1KDM4EMAPTTDP1ABCG2 | |
| SCHEMBL23295219 | 0.67 | TNFRSF1A (0.64) | TNFRSF1AALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL14947393 | 0.67 | TNFRSF1A (0.82) | TNFRSF1AABCB1ABCG2TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | disclosed |