Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4598673 | 0.77 | CHRNB2 (0.37) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA7 | |
| SCHEMBL3990466 | 0.74 | — | — | |
| SCHEMBL1132078 | 0.73 | — | — | |
| SCHEMBL9043577 | 0.72 | CES2 (0.50) | ALDH1A1RAB9A | |
| SCHEMBL9959799 | 0.72 | EPHX2 (0.41) | CHRNB2CHRNB4CHRNA3CHRNA4LMNA | |
| SCHEMBL8418414 | 0.72 | TSHR (0.32) | — | |
| SCHEMBL15467085 | 0.72 | EPHX2 (0.41) | CHRNB2CHRNB4CHRNA3CHRNA4LMNA | |
| SCHEMBL853291 | 0.72 | EPHX2 (0.41) | CHRNB2CHRNB4CHRNA3CHRNA4LMNA | |
| SCHEMBL854725 | 0.72 | EPHX2 (0.41) | CHRNB2CHRNB4CHRNA3CHRNA4LMNA | |
| SCHEMBL4437402 | 0.72 | CES2 (0.50) | ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |