SCHEMBL8550799

SCHEMBL8550799

FC(F)(F)c1cccc(Oc2cc(Cl)cc(OCc3ccsc3)n2)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.45
POLB P06746 2/20 0.45
ALDH1A1 P00352 1/20 0.42
MRGPRX4 Q96LA9 1/20 0.40
LMNA P02545 1/20 0.40
PKM P14618 1/20 0.40
HSD17B10 Q99714 1/20 0.40
NTRK1 P04629 2/20 0.40
MAPT P10636 2/20 0.39
NR4A2 P43354 1/20 0.38
PLA2G7 Q13093 1/20 0.38
GAA P10253 2/20 0.37
NPSR1 Q6W5P4 2/20 0.37
KDM4E B2RXH2 1/20 0.37
MAPK1 P28482 1/20 0.37
P2RY1 P47900 1/20 0.37
LOX P28300 1/20 0.37
LOXL2 Q9Y4K0 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2C9 P11712 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8545000 0.92 L3MBTL1 (0.47) L3MBTL1POLBALDH1A1MRGPRX4LMNA
SCHEMBL8546028 0.89 L3MBTL1 (0.45) L3MBTL1POLBALDH1A1MRGPRX4LMNA
SCHEMBL8547073 0.89 L3MBTL1 (0.48) L3MBTL1POLBALDH1A1MRGPRX4LMNA
SCHEMBL8546656 0.88 L3MBTL1 (0.45) L3MBTL1POLBALDH1A1MRGPRX4LMNA
SCHEMBL8545730 0.88 L3MBTL1 (0.44) L3MBTL1POLBALDH1A1MRGPRX4LMNA
SCHEMBL8545122 0.87 POLB (0.43) L3MBTL1POLBALDH1A1MRGPRX4LMNA
SCHEMBL8550496 0.87 L3MBTL1 (0.43) L3MBTL1POLBALDH1A1MRGPRX4LMNA
SCHEMBL8550416 0.87 L3MBTL1 (0.43) L3MBTL1POLBALDH1A1MRGPRX4LMNA
Pyridine SCHEMBL8827987 0.84 L3MBTL1 (0.45) L3MBTL1POLBALDH1A1MRGPRX4LMNA
SCHEMBL8773192 0.81 MAPT (0.52) L3MBTL1POLBALDH1A1NTRK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0693490-B1 2-Phenoxy-6-thienylmethyloxypyridine derivative, process for producing the same, and herbicidal composition KUREHA CHEMICAL IND CO LTD (JP) 1998-09-09 EP disclosed
US-5624942-A 2-phenoxy-6-thienylmethyloxypyridine derivative and herbicidal composition containing same KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1997-04-29 US disclosed
EP-0693490-A1 2-Phenoxy-6-thienylmethyloxypyridine derivative, process for producing the same, and herbicidal composition KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1996-01-24 EP disclosed