Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.56 |
| ▸ | FAAH | O00519 | 3/20 | 0.54 |
| ▸ | CES1 | P23141 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20378794 | 0.98 | MAPT (0.67) | MAPTRXFP1HDAC1HDAC2HDAC3 | |
| SCHEMBL12813508 | 0.98 | MAPT (0.67) | MAPTRXFP1HDAC1HDAC2HDAC3 | |
| SCHEMBL8102562 | 0.98 | MAPT (0.67) | MAPTRXFP1HDAC1HDAC2HDAC3 | |
| SCHEMBL7076078 | 0.94 | HDAC1 (0.64) | MAPTRXFP1HDAC1HDAC2HDAC3 | |
| SCHEMBL4886613 | 0.88 | MAPT (0.73) | MAPTRXFP1HDAC1HDAC2HDAC3 | |
| SCHEMBL11137519 | 0.86 | MAPT (0.77) | MAPTRXFP1HDAC1HDAC2HDAC3 | |
| SCHEMBL1508071 | 0.86 | MAPT (0.77) | MAPTRXFP1HDAC1HDAC2HDAC3 | |
| SCHEMBL191218 | 0.86 | KEAP1 (0.61) | MAPTRXFP1HDAC1HDAC2HDAC3 | |
| SCHEMBL28609434 | 0.86 | MAPT (0.77) | MAPTRXFP1HDAC1HDAC2HDAC3 | |
| SCHEMBL19625551 | 0.84 | MAPT (0.68) | MAPTRXFP1HDAC1HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180201592-A1 | 2-AMINO-1,3,4-THIADIAZINE AND 2-AMINO-1,3,4-OXADIAZINE BASED ANTIFUNGAL AGENTS | F2G LIMITED (GB) | 2018-07-19 | — | — | US | disclosed |
| EP-0865429-A1 | AZETIDINONE COMPOUNDS FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997021676-A1 | AZETIDINONE COMPOUNDS FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180201592-A1 | 2-AMINO-1,3,4-THIADIAZINE AND 2-AMINO-1,3,4-OXADIAZINE BASED ANTIFUNGAL AGENTS | NAT1, DPM1, IL4I1 | MAPT 103/4885RXFP1 3439/4885HDAC1 2572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.