Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.52 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8556948 | 0.99 | BCHE (0.58) | BCHEOPRK1ADRB2SIGMAR1L3MBTL1 | |
| SCHEMBL8550920 | 0.94 | ATM (0.58) | BCHEOPRK1ADRB2SIGMAR1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL8554513 | 0.93 | ATM (0.57) | BCHEOPRK1ADRB2SIGMAR1L3MBTL1 | |
| SCHEMBL8550490 | 0.88 | BCHE (0.65) | BCHEOPRK1MEN1KMT2ADRD2 | |
| Hydrochloric Acid SCHEMBL8556315 | 0.87 | MEN1 (0.65) | BCHEOPRK1MEN1KMT2ADRD2 | |
| SCHEMBL8551771 | 0.87 | SIGMAR1 (0.65) | BCHEOPRK1SIGMAR1L3MBTL1MEN1 | |
| SCHEMBL8551618 | 0.87 | OPRK1 (0.56) | BCHEOPRK1MEN1KMT2AKDM4E | |
| SCHEMBL8549751 | 0.87 | KMT2A (0.65) | BCHEOPRK1SIGMAR1MEN1KMT2A | |
| SCHEMBL8550677 | 0.87 | OPRK1 (0.61) | BCHEOPRK1SIGMAR1L3MBTL1MEN1 | |
| SCHEMBL8554249 | 0.87 | KMT2A (0.65) | BCHEOPRK1SIGMAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1084329-C | Benzyl piepridine derivs as pharmaceutical agents | HOFFMANN LA ROCHE (CH) | 2002-05-08 | — | — | CN | disclosed |
| EP-0871613-A1 | BENZYL PIPERIDINE DERIVATIVES AS PHARMACEUTICAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 1998-10-21 | — | — | EP | disclosed |
| CN-1183768-A | Benzyl piepridine derivs as pharmaceutical agents | HOFFMANN LA ROCHE (CH) | 1998-06-03 | — | — | CN | disclosed |
| US-5753679-A | SCIZOPHRENIA | HOFFMANN-LA ROCHE INC. (US) | 1998-05-19 | — | — | US | disclosed |
| WO-1996035666-A1 | BENZYL PIPERIDINE DERIVATIVES AS PHARMACEUTICAL AGENTS | F.HOFFMANN-LA ROCHE AG (CH) | 1996-11-14 | — | — | WO | disclosed |