Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.45 |
| ▸ | ITGAV | P06756 | 17/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7402861 | 0.82 | ITGB3 (0.67) | ITGB3ITGAVITGA2B | |
| SCHEMBL8548718 | 0.79 | ITGB3 (0.41) | ITGB3ITGAVITGA2B | |
| SCHEMBL7347915 | 0.74 | ITGB3 (0.46) | ITGB3ITGAVITGA2B | |
| SCHEMBL7400652 | 0.74 | ITGB3 (0.67) | ITGB3ITGAVITGA2B | |
| SCHEMBL8177321 | 0.71 | ITGB3 (0.42) | ITGB3ITGAVITGA2B | |
| SCHEMBL8643943 | 0.69 | ITGB3 (0.36) | ITGB3ITGAVITGA2B | |
| SCHEMBL7396575 | 0.68 | ITGB3 (0.43) | ITGB3ITGAVITGA2B | |
| SCHEMBL7406112 | 0.68 | ITGB3 (0.65) | ITGB3ITGAVITGA2B | |
| SCHEMBL7401937 | 0.68 | ITGB3 (0.51) | ITGB3ITGAVITGA2B | |
| SCHEMBL7347802 | 0.67 | ITGB3 (0.38) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828737-A1 | ISOXAZOLINE AND ISOXAZOLE DERIVATIVES AS INTEGRIN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-03-18 | — | — | EP | disclosed |