Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 11/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551014 | 0.87 | PTGS2 (0.41) | PTGS2PTGS1TP53 | |
| SCHEMBL8551355 | 0.85 | PTGS2 (0.50) | PTGS2PTGS1S1PR1S1PR3 | |
| SCHEMBL8551144 | 0.85 | ERN1 (0.42) | PTGS2PTGS1TP53 | |
| SCHEMBL8548972 | 0.84 | PTGS2 (0.42) | PTGS2PTGS1TP53CA1CA2 | |
| SCHEMBL9098556 | 0.84 | PTGS2 (0.38) | PTGS2PTGS1TP53 | |
| SCHEMBL8549867 | 0.84 | PTGS2 (0.38) | PTGS2PTGS1TP53 | |
| SCHEMBL8551034 | 0.81 | PTGS2 (0.42) | PTGS2PTGS1 | |
| SCHEMBL8551146 | 0.80 | PTGS2 (0.40) | PTGS2PTGS1TP53 | |
| SCHEMBL8548704 | 0.79 | PTGS2 (0.43) | PTGS2PTGS1TP53 | |
| SCHEMBL8547371 | 0.78 | PTGS2 (0.47) | PTGS2PTGS1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825989-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-03-04 | — | — | EP | disclosed |