Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 11/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8546693 | 0.87 | PTGS2 (0.46) | PTGS2PTGS1 | |
| SCHEMBL8551018 | 0.85 | PTGS2 (0.41) | PTGS2PTGS1S1PR1S1PR3 | |
| SCHEMBL8548972 | 0.85 | PTGS2 (0.42) | PTGS2PTGS1 | |
| SCHEMBL8548704 | 0.84 | PTGS2 (0.43) | PTGS2PTGS1 | |
| SCHEMBL8552225 | 0.82 | PTGS2 (0.46) | PTGS2PTGS1 | |
| SCHEMBL8547371 | 0.82 | PTGS2 (0.47) | PTGS2PTGS1 | |
| SCHEMBL8552226 | 0.81 | PTGS2 (0.47) | PTGS2PTGS1 | |
| SCHEMBL8547373 | 0.81 | PTGS2 (0.46) | PTGS2PTGS1 | |
| SCHEMBL9098556 | 0.80 | PTGS2 (0.38) | PTGS2PTGS1 | |
| SCHEMBL8551146 | 0.80 | PTGS2 (0.40) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825989-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-03-04 | — | — | EP | disclosed |