Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.40 |
| ▸ | PRCP | P42785 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27476952 | 0.90 | TRPV1 (0.50) | HPGDNAMPTASAH1EPHX2ALDH1A1 | |
| SCHEMBL27495124 | 0.90 | TRPV1 (0.50) | HPGDNAMPTASAH1EPHX2ALDH1A1 | |
| SCHEMBL8440276 | 0.90 | TRPV1 (0.50) | HPGDNAMPTASAH1EPHX2ALDH1A1 | |
| SCHEMBL8441268 | 0.90 | TRPV1 (0.50) | HPGDNAMPTASAH1EPHX2ALDH1A1 | |
| SCHEMBL8440280 | 0.90 | TRPV1 (0.50) | HPGDNAMPTASAH1EPHX2ALDH1A1 | |
| SCHEMBL8442701 | 0.89 | TRPV1 (0.48) | HPGDNAMPTASAH1EPHX2ALDH1A1 | |
| SCHEMBL8102617 | 0.88 | HPGD (0.49) | HPGDPOLBEPHX2ALDH1A1 | |
| SCHEMBL8592437 | 0.87 | LMNA (0.44) | HPGDNAMPT | |
| SCHEMBL8441910 | 0.86 | TRPV1 (0.55) | HPGDALDH1A1 | |
| SCHEMBL8591482 | 0.85 | TRPV1 (0.45) | HPGDNAMPTASAH1EPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865429-A1 | AZETIDINONE COMPOUNDS FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997021676-A1 | AZETIDINONE COMPOUNDS FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-06-19 | — | — | WO | disclosed |