Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555702 | 0.85 | — | — | |
| SCHEMBL6829492 | 0.79 | F2 (0.35) | NR1H2 | |
| SCHEMBL6647089 | 0.78 | MIF (0.34) | HDAC1HDAC8HDAC6APP | |
| SCHEMBL6075300 | 0.72 | PDK4 (0.30) | — | |
| SCHEMBL7261773 | 0.71 | CYP11B1 (0.38) | NR1H2APP | |
| SCHEMBL14638189 | 0.69 | MAPT (0.41) | NR1H2 | |
| SCHEMBL30659307 | 0.69 | MAPK1 (0.34) | — | |
| SCHEMBL6824480 | 0.68 | KDM4E (0.38) | HDAC1HDAC6 | |
| SCHEMBL6222079 | 0.68 | KDM4E (0.40) | — | |
| SCHEMBL29744751 | 0.68 | PDK4 (0.54) | NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0856002-A1 | PHENYLOXAZOLIDINONES HAVING A C-C BOND TO 4-8 MEMBERED HETEROCYCLIC RINGS | PHARMACIA & UPJOHN COMPANY (US) | 1998-08-05 | — | — | EP | disclosed |
| WO-1997009328-A1 | PHENYLOXAZOLIDINONES HAVING A C-C BOND TO 4-8 MEMBERED HETEROCYCLIC RINGS | PHARMACIA & UPJOHN COMPANY (US) | 1997-03-13 | — | — | WO | disclosed |