⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551150 | 0.85 | NR1H2 (0.33) | — | |
| SCHEMBL6647089 | 0.78 | MIF (0.34) | — | |
| SCHEMBL6829492 | 0.77 | F2 (0.35) | — | |
| SCHEMBL7261773 | 0.72 | CYP11B1 (0.38) | — | |
| SCHEMBL18631829 | 0.71 | CASP1 (0.30) | — | |
| SCHEMBL6824480 | 0.68 | KDM4E (0.38) | — | |
| SCHEMBL1459947 | 0.68 | MAPK1 (0.34) | — | |
| SCHEMBL7527330 | 0.68 | MAPT (0.41) | — | |
| SCHEMBL6075300 | 0.68 | PDK4 (0.30) | — | |
| SCHEMBL4427892 | 0.68 | CRBN (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0856002-A1 | PHENYLOXAZOLIDINONES HAVING A C-C BOND TO 4-8 MEMBERED HETEROCYCLIC RINGS | PHARMACIA & UPJOHN COMPANY (US) | 1998-08-05 | — | — | EP | disclosed |
| WO-1997009328-A1 | PHENYLOXAZOLIDINONES HAVING A C-C BOND TO 4-8 MEMBERED HETEROCYCLIC RINGS | PHARMACIA & UPJOHN COMPANY (US) | 1997-03-13 | — | — | WO | disclosed |