Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 18/20 | 0.51 |
| ▸ | CA9 | Q16790 | 16/20 | 0.51 |
| ▸ | CA12 | O43570 | 12/20 | 0.51 |
| ▸ | CA1 | P00915 | 16/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5763086 | 0.87 | CA2 (0.47) | CA2CA9CA12CA1CA7 | |
| SCHEMBL8149304 | 0.82 | CA2 (0.55) | CA2CA9CA12CA1CA7 | |
| SCHEMBL8153130 | 0.80 | CA2 (0.55) | CA2CA9CA12CA1CA7 | |
| SCHEMBL13335153 | 0.77 | AKR1B1 (0.59) | AKR1B1 | |
| SCHEMBL5761886 | 0.76 | CA2 (0.46) | CA2CA9CA12CA1CA7 | |
| SCHEMBL8152917 | 0.76 | PTGS2 (0.42) | PTGS2 | |
| SCHEMBL15560613 | 0.74 | CA2 (0.62) | CA2CA9CA12CA1CA14 | |
| SCHEMBL6758639 | 0.71 | AKR1B1 (0.50) | AKR1B1 | |
| SCHEMBL8146467 | 0.71 | CA2 (0.53) | CA2CA9CA12CA1CA7 | |
| SCHEMBL8138559 | 0.70 | PTGS2 (0.47) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825989-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-03-04 | — | — | EP | disclosed |