Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551225 | 1.00 | LMNA (0.39) | LMNAITGB3ITGA2BCHRM4CHRM2 | |
| Bromide SCHEMBL8551655 | 0.99 | LMNA (0.38) | LMNAITGB3ITGA2BCHRM4CHRM2 | |
| Bromide SCHEMBL8592755 | 0.89 | LMNA (0.37) | LMNACHRM4CHRM2CHRM1GAA | |
| SCHEMBL8550368 | 0.80 | SMYD3 (0.40) | ITGB3ITGA2BDGAT1ALDH1A1 | |
| SCHEMBL8550362 | 0.80 | SMYD3 (0.40) | ITGB3ITGA2BDGAT1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8551138 | 0.79 | SMYD3 (0.40) | ITGB3ITGA2BDGAT1ALDH1A1 | |
| SCHEMBL8549817 | 0.78 | ITGB3 (0.42) | ITGB3ITGA2BCRHR1 | |
| SCHEMBL8550491 | 0.78 | SMYD3 (0.41) | ITGB3ITGA2B | |
| SCHEMBL8549822 | 0.78 | ITGB3 (0.42) | ITGB3ITGA2BCRHR1 | |
| SCHEMBL8550484 | 0.78 | SMYD3 (0.41) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858457-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | Dr. Karl Thomae GmbH (DE) | 1998-08-19 | — | — | EP | claimed |
| WO-1997015567-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | DR. KARL THOMAE GMBH (DE) | 1997-05-01 | — | — | WO | claimed |